Skip to primary content

The CHOICE project was initiated and is run from Denmark, but has since expanded and now has partners in both Sweden and Norway

Consortium partners

   
  Professor
Katrine Hass Rubin
Professor, Senior Consultant (MD)
Mattias Lorentzon
Professor, MD
Mari Hoff
 
   
 
 

Project team

 
Professor, consultant 
Bo Abrahamsen
MD/PhD/Professor, GP, Clin.Pharm
Jens Søndergaard
Professor
Uffe Kock Wiil
 
   

PhD
Jan Christian Brønd

Associate Professor
Pernille Ravn Jakobsen

Postdoc / Nurse
Anne Wettergren Karlsson
 

 

Postdoc
Jens-Jakob Møller

PhD
Line M. Nanque

Ph.d. student, MScPH
Emilie R. Christensen
 

   
MD / PhD / Postdoc / Professor  MSc, MD, PhD, Post-doc
Kristian Axelsson
 Assistant Professor (Biträdande lektor)
Sebastian Lindblom
   

     
Associate Professor, MD
Julie Horn
     

 

Read more about the individual team members

 

 
The danish team members

Professor
Katrine Hass Rubin

Odense University Hospital and University of Southern Denmark (Research unit OPEN)

Area(s) of research / Field of interest
Main area of research is osteoporosis and bone fractures, with a focus on optimizing their identification and prevention. Katrine leads the CHOICE project and is the principal investigator of the NordForsk-funded grant. Her work centers on developing automated, data-driven prediction models using national health registry data, with a particular focus on implementation in clinical practice.

Background / Experience
With a background in Physiotherapy (1999) and a PhD in Epidemiology (2013), she has published over 100 peer-reviewed papers. She serves on the board of the Danish Bone Society and is a member of the Committee of Scientific Advisors at the International Osteoporosis Foundation.

 

Professor, consultant
Bo Abrahamsen

Holbæk Hospital and University of Southern Denmark

Area(s) of research / Field of interest
Bone clinician whose area of research is fracture and lifecourse epidemiology, risk prediction algorithms, and the safety and effectiveness of osteoporosis treatments. He leads the national NOCTE initiative, which combines DXA, hospital, prescription, and biochemical data to model BMD trajectories and fracture risk. His work supports individual and societal data-driven strategies for improving osteoporosis diagnosis and care.

Background / Experience
Bo is a Consultant Endocrinologist (DK and UK accredited) at Holbæk Hospital and Professor of Clinical Database Research at the University of Southern Denmark. He trained in medicine in Odense, Denmark, with additional research experience from the UK and the US. He held a visiting professorship at the University of Oxford and served as President of the European Calcified Tissue Society (2020–2023).

MD/PhD/Professor, GP, Clin.Pharm
Jens Søndergaard

Research Unit of General Practice, University of Southern Denmark

Area(s) of research / Field of interest
Osteoporosis, risks, use of data for early detection of disease, primary care. 

Background / Experience
I have over 25 years of research experience and have authored numerous publications in various fields, the majority of which are relevant to primary health care.

Professor
Uffe Kock Wiil

SDU Health Informatics and Technology, The Maersk Mc-Kinney Moller Institute, University of Southern Denmark

Area(s) of research / Field of interest
Data-driven health technology including  intelligent monitoring and decision support; predictive models for prevention, early detection, diagnosis, treatment and prognosis; digital health systems offering novel personalized data collection, treatment plans and interventions.

Background / Experience
Implementation of clinical decision support systems with a holistic approach including user involvement (co-design as overall approach), AI (develop models), software engineering (develop decision support based on models), health informatics (integration with health IT systems).

PhD
Jan Christian Brønd

OUH/Open

Area(s) of research / Field of interest
Specialized in the development and implementation of machine learning methods within the healthcare domain, with a particular focus on creating optimal solutions through the effective use of clinical, registry, and sensor data.

Background / Experience
Strong experience in developing software for health application in the industry and data science within academic research.

 Associate Professor
Pernille Ravn Jakobsen

Odense University Hospital & University of Southern Denmark (Research Unit OPEN)

 

Area(s) of research / Field of interest
My research focuses on the design, development, and testing of data-driven health technologies that strengthen self-management in patients with osteoporosis and help reduce fracture risk. I work with participatory design, combining qualitative and quantitative methods to identify user needs and involving patients, healthcare professionals, and stakeholders in iterative processes that create solutions ready for implementation in healthcare systems. 

Background / Experience
I am a physiotherapist with a Master of Science in Public Health and a PhD. In my PhD, I developed and tested an app for patients with osteoporosis as an entrepreneur. The app was later implemented in Danish clinical guidelines and has since been downloaded by more than 30,000 patients. Today, I am back in research, driven by the same motivation: creating change for patients with osteoporosis by optimizing prediction and prevention.

Postdoc / Nurse
Anne Wettergren Karlsson

Center for Research With Patients and Relatives, OPEN

Area(s) of research / Field of interest
I work with patient and public involvement in research, and my field of interest is on how we establish ongoing and meaningful collaborations between users and researchers. My role in CHOICE is to plan our different collaborations with public contributors and carry out workshops exploring user perspectives and needs in osteoporosis management. 

Background / Experience
I am a nurse, and have experience from neurology and palliation. In my previous research, I have explored user perspectives on health data usage for research and investigated how patient and public involvment practices are experienced in Denmark. I also council other researchers on meaningfull involvement practices. 

Postdoc
Jens-Jakob Møller 

Postdoc at Research Unit OPEN 

Area(s) of research / Field of interest
I am interested in epidemiology and methodology. I strive to learn more and wish to develop my skills constantly. My main interest is registry studies with the abilities of large cohorts, comprehensive data and full follow-up.

Background / Experience
My background is in physiotherapy. After my register-based PhD, I have been a consultant for other researchers in the area of epidemiology and register-based studies. 

PhD
Line M. Nanque

OPEN, Odense University Hospital, Region of Southern Denmark

Area(s) of research / Field of interest
I am interested in how data can be used to promote health and prevent diseases. My role in CHOICE is to coordinate the project activities across Denmark, Sweden and Norway. Furthermore, I will support the harmonization of registry data and development of a common data model, which can build the foundation for evaluation of the predictive capabilities of FREM_ML in the Nordic countries.

Background / Experience
I hold a PhD in vaccine epidemiology in Guinea-Bissau, West Africa. In this research, I investigated the non-specific effects of polio vaccines on general child health. 

 

Ph.d. student, MScPH
Emilie R. Christensen

Research Unit OPEN, Odense University Hospital, Region of Southern Denmark and Department of Clinical Research, University of Southern Denmark

Area(s) of research / Field of interest
Main field of interest is implementation of digital health technologies in healthcare settings. Emilie’s work centers on the feasibility of implementing prediction models in primary healthcare, with a focus on both technical validation and exploring how these technologies fit into general practice from healthcare professionals’ and patients’ perspectives. 

Background / Experience
Emilie has a background in medical laboratory science (2018) and a MSc in public health (2021), and is currently working as a Ph.D. student. She has been working with osteoporosis and fracture risk prediction models since 2022.


The swedish team members

Professor, Senior Consultant (MD)
Mattias Lorentzon

University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden

Area(s) of research / Field of interest
Fracture risk prediction and prevention. Osteoporosis treatment. Osteoporosis and fracture risk factors. 

Background / Experience
Professor, senior consultant in geriatric medicine, with over 25 years of experience in osteoporosis research. Over 350 peer-reviewed publication, of which most are in the osteoporosis and fracture research field.

MD / PhD / Postdoc / Professor  MSc, MD, PhD, Post-doc
Kristian Axelsson

Geriatric medicin, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg

 

Area(s) of research / Field of interest
Fracture risk, fracture liaison services, epidemiology, machine learning

Background / Experience
Previously IT-entrepreneur. Now clinically active in primary care. Chairs the regional clinical osteoporosis group in Western Sweden (VGR) since several years and has contributed to the latest national guidelines from the Swedish Osteoporosis Society, National Board of Health and Welfare and the Swedish Association of Local Authorities and Regions (SKR).

Assistant Professor
(Biträdande lektor)
Sebastian Lindblom

Mälardalen University / Karolinska Institutet and Karolinska University Hospital

Area(s) of research / Field of interest
My research focuses on person-centred integrated care, particularly how healthcare can strengthen individuals’ ability to self-care and how services can be organized to be more coordinated and cohesive from the individual’s perspective. The aim is to support and improve the health and daily lives of people living with long-term disabilities and their families.

Background / Experience
I am a registered physiotherapist with a PhD and experience in both qualitative and quantitative research. My work focuses on care transitions, care coordination, and the development of person-centred integrated models of care and rehabilitation through co-design. Extensive experience with patient and public involvement in research.


The norwegian team members

Professor, MD
Mari Hoff

Area(s) of research / Field of interest
Most of my research is based on the HUNT population study. My two main areas of focus are osteoporosis and psoriatic arthritis. In addition, I have conducted several studies on physical activity in patients with inflammatory arthritis.

Background / Experience
Cand. Med. 1993. Rheumatologist since 2003. Professor of rheumatology 2020.

Associate Professor, MD
Julie Horn

HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology, Levanger, Norway

Department of Obstetrics and Gynecology, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway 

Area(s) of research / Field of interest
Research focuses on women’s health across the life course and includes topics such as the long-term effects of early-life adversity, pregnancy complications, postpartum health, and osteoporosis.

Background / Experience
Associate professor, consultant in gynecology and obstetrics, with experience in quantitative and qualitative research, in depth knowledge of the HUNT cohort and lifecourse epidemiology. 

APPFWU02V